According to an article published today in Front Line Genomics, drug industry leader Pfizer will no longer pursue research into Alzheimer’s (AD)and Parkinson’s (PD) Diseases. The announcement comes on the heels of several failed trials of their own and other Big Pharma drugs for these devastating conditions.
Pfizer faced a major setback in 2012 when the company and its partner, Johnson & Johnson decided to discontinue the development of bapineuzumab IV following a late-stage failure. Eli Lilly and Company and Merck have also
been unable to develop treatments for Alzheimer’s. Lilly, after disappointing results in a late-stage study, decided in November 2016 to abandon its AD treatment, solanezumab. Merk’s AD potential drug, verubecestat, was halted in the EPOCH Phase II/III study in February 2017 after it was determined the study might fail. Another ongoing study is expected to report out in February 2019. Another drug company, Biogen, suffered a recent setback when it was found its experimental drug did not meet criteria for success. Axovant Sciences also had a major setback in September 2017 when its AD drug candidate failed to meet the endpoints in a late-stage study.
This leaves people who live with these diseases with only a few new prescription medications in the drug pipeline. Biogen’s aducanumab is in a couple of late-stage studies. Biogen is also working on elenbecestat, a genetics-based drug in a Phase III program in collaboration with Eisai. Lilly has several AD candidates in its pipeline, including lanabecestat, developed with AstraZeneca. Novartis and Amgen are collaborating on a similar genetics-based drug, while Roche is collaborating with AC Immune in the development of AD treatments (Source).
Fortunately, there are recent findings in the areas of natural health for both brain-related diseases. Tai Chi and QiGong improve physical function, depression, and quality of life in people with PD. Coconut oil can help improve brain function in women with AD.
Let me know in the comments below if you would like more information about non-drug treatments for these and other chronic diseases.
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